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Strain Registration

Strain: SD-Tg(HRAS)128Ncc

Symbol: SD-Tg(HRAS)128Ncc
Strain: SD-Tg(HRAS)128
Substrain: Ncu
RGD ID: 2304330
Citation ID: RRID:RGD_2304330
Ontology ID: RS:0002124
Also Known As: Hras128; NBRP Rat No: 0376; SD-Tg(HRAS)128Htsu; SD-Tg(HRAS)128Ncu
Type: transgenic
Available Source: National BioResource Project for the Rat in Japan
Origination: National BioResource Project for the Rat in Japan
Description: This strain is carrying three copies of the human c-Ha-ras proto-oncogene, including its own promoter region.
Coat Color: Albino
Last Known Status: Cryopreserved Embryo; Cryopreserved Sperm (as of 2021-04-30)
Research Usage Cancer






References

References - curated
# Reference Title Reference Citation
1. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines
3. High susceptibility of human c-Ha-ras proto-oncogene transgenic rats to carcinogenesis: a cancer-prone animal model. Tsuda H, etal., Cancer Sci. 2005 Jun;96(6):309-16.

Region


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_life_disease The rats are extremely sensitive to the induction of mammary carcinomas induced by chemical carcinogen such as DMBA and MNU. 1302502
strain_reproduction Maintained as heterozygous males. 1302502

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-04-30 SD-Tg(HRAS)128Ncc    SD-Tg(HRAS)128Ncu    Symbol and/or name change 68913 APPROVED
2012-05-16 SD-Tg(HRAS)128Ncu    SD-Tg(HRAS)128Ncu    Name updated 68913 APPROVED
2012-05-16 SD-Tg(HRAS)128Ncu    SD-Tg(HRAS)128Ncu    Name updated 68913 APPROVED